Mecop - OD

indications

01

Peripheral Diabetic Neuropathy

02

Fibromyalgia Syndrome

03

Spinal Cord Injury

04

Post Herpetic Neuralgia

05

Drug Induced Neuropathy

06

Bell's Palsy

07

Trigeminal Neuralgia

INFORMATION ABOUT METHYLCOBALAMIN + PREGABALIN

Methylcobalamin + Pregabalin Uses

Methylcobalamin+Pregabalin are used in the treatment of neuropathic pain.

How Methylcobalamin + Pregabalin works

Methylcobalamin + Pregabalin are a combination of two medicines: Methylcobalamin and Pregabalin. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).

Common side effects of Methylcobalamin + Pregabalin

Dizziness, Sleepiness, Tiredness, Uncoordinated body movements

EXPERT ADVICE FOR METHYLCOBALAMIN + PREGABALIN

  • You have been prescribed Methylcobalamin + Pregabalin for treating and preventing nerve pain.
  • Its side effects are usually mild and temporary.
  • It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • To lower the chances of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Avoid consuming alcohol when taking Methylcobalamin + Pregabalin, as it may cause excessive sleepiness.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor.

FREQUENTLY ASKED QUESTIONS FOR METHYLCOBALAMIN + PREGABALIN

  • What isMethylcobalamin+Pregabalin?Open or Close

    Methylcobalamin+Pregabalinis a combination of two medicines: Pregabalin and Methylcobalamin. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.

  • Can I stop taking Methylcobalamin+Pregabalin when my pain is relieved?Open or Close

    No, you should not stop taking Methylcobalamin+Pregabalin even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Methylcobalamin+Pregabalin, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the use of Methylcobalamin+Pregabalin before you stop the medication completely.

  • How to manage weight gain associated with the use of Methylcobalamin+Pregabalin?Open or Close

    Methylcobalamin+Pregabalin can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.

  • Can the use of Methylcobalamin+Pregabalin cause sleepiness or drowsiness?Open or Close

    Yes, Methylcobalamin+Pregabalin may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.

  • Are there any serious side effects associated with the use of Methylcobalamin+Pregabalin?Open or Close

    Serious side effects caused because of the use of Methylcobalamin+Pregabalin are uncommon and rare. However, it may cause serious side effects like allergic reaction, suicidal thoughts or swelling of limbs (hands, legs or feet). Stop taking Methylcobalamin+Pregabalin and contact your doctor if you have any signs of these serious side effects. Signs of an allergic reaction include swelling of your face, mouth, lips, gums, tongue and neck. Allergic reactions can also lead to trouble in breathing, skin rash, hives (raised bumps) or blisters. Pay attention to any changes, especially sudden changes in mood, behaviors, thoughts or feelings, or if you have suicidal thoughts.

  • How long will the Methylcobalamin+Pregabalin take to act?Open or Close

    An initial benefit with Methylcobalamin+Pregabalin may be seen after 2 weeks of treatment. However, it may take around 2-3 months or more (in some patients) to see the full benefits.

  • What if I forget to take Methylcobalamin+Pregabalin?Open or Close

    If you forget to take the scheduled dose of Methylcobalamin+Pregabalin and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects. If you are not sure what to do, consult your doctor about how to manage a situation like this.

  • Will a higher than the recommended dose of Methylcobalamin+Pregabalin be more effective?Open or Close

    No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

  • Can I drink alcohol while taking Methylcobalamin+Pregabalin?Open or Close

    No, do not drink alcohol while taking Methylcobalamin+Pregabalin. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Methylcobalamin+Pregabalin.

  • How often should I see the doctor?Open or Close

    You may need to see your doctor regularly if you have started to take Methylcobalamin+Pregabalin. However, you must consult your doctor if the advised dosage of Methylcobalamin+Pregabalin does not improve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.

  • Are there any special instructions regarding storage and disposal of this medicine?Open or Close

    Keep your tablets in the pack until it is time to take them. Store them in a cool dry place. Store them out of sight and reach of children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

AVAILABLE MEDICINE FOR METHYLCOBALAMIN + PREGABALIN

  • Pxxxeb MTorrent Pharmaceuticals Ltd - 168  to  303
  • Prxxxxin MTorrent Pharmaceuticals Ltd - 251  to  302
  • Mxxxxxin MSun Pharmaceutical Industries Ltd - 127  to  258
  • Pxxxxxa-MTorrent Pharmaceuticals Ltd - 123  to  296
  • Nexxxxa MSun Pharmaceutical Industries Ltd - 114  to  270
  • Rxxxn MEris Lifesciences Ltd - 148  to  260
MRP of Mecop-OD - Rs.190/-

Advantages of Mecop- OD over other dosage forms of Pregabalin and Methylcobalamin combination

  • Mecop-OD is the first Softgel brand of Pregabalin + Methylcobalamin in India.
  • Mecop- OD has highest bioavailability as compared to any other dosage form.
  • Mecop- OD has the OD dose convenience.
  • Mecop- OD is more compliant form where taste and odour is being masked off.
  • Mecop- OD has faster onset of action.
  • Mecop- OD is non-sedative because of Sustain release technology.
  • Mecop- OD with such technology and new dosage form, it has a very nominal price as compare to the market.

SIDE EFFECTS OF MECOP-OD SOFTGEL

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

Common side effects of Mecop-OD

  • Dizziness
  • Sleepiness
  • Tiredness
  • Uncoordinated body movements

SAFETY ADVICE

Alcohol

UNSAFE

Mecop-OD Softgel may cause excessive drowsiness with alcohol.

Driving

UNSAFE

Mecop-OD Softgel may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Breast feeding

CONSULT YOUR DOCTOR

Mecop-OD Softgel is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breast milk and harm the baby.

Liver

SAFE IF PRESCRIBED

Mecop-OD Softgel is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Mecop-OD Softgel may not be needed in these patients. Please consult your doctor.

Kidney

CAUTION

Mecop-OD Softgel should be used with caution in patients with kidney disease. Dose adjustment of Mecop-OD Softgel may be needed. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Mecop-OD Softgel may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

DOWNLOAD RESEARCH PAPERS
Pregabalin in DPN
Sustain release pregabalin
Vitamin b12 or methylcobalamin
Efficacy and Tolerability of a Fixed Dose Combinat
Posthoracotomy pain treated with pregabalin and methylcobalamin

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